Blood Cell Analysis: From Traditional Methods to Super-Resolution Microscopy

Blood cell analysis is essential for the diagnosis and identification of hematological malignancies. The use digital microscopy systems has been extended in clinical laboratories. Super-resolution (SRM) attracted wide attention medical field due to its nanoscale spatial resolution high sensitivity. It considered be a potential method blood that may have more advantages than traditional approaches such as conventional optical hematology analyzers certain examination projects. In this review, we firstly summarize several common technologies clinic, analyze disadvantages these technologies. Then, focus on basic principles characteristics three representative SRM techniques, well latest advances techniques analysis. Finally, discuss developmental trend possible research directions SRM, provide some discussions further development